Selected publications: (*corresponding author)

    [54] Chen G. B.*, Xia B., Fu Q., Huang X., Wang F. P., Chen Z. M.*, Lv Y. G.*, Matrix mechanics as regulatory factors and therapeutic targets in hepatic fibrosis, International Journal of Biological Sciences, in press, 2019. (IF=4.067)

    [53] Wang Y., Zhang X. M., Zhao B. Y., Xu Z. L.*, Lv Y. G.*, Suspension state promotes drug resistance of breast tumor cells by inducing ABCC3 overexpression, Applied Biochemistry and Biotechnology, in press, 2019.

    [52] Xia B., Chen G. B., Zou Y., Yang L., Pan J., Lv Y. G.*, Low-intensity pulsed ultrasound combination with induced pluripotent stem cells-derived neural crest stem cells and growth differentiation factor 5 promotes sciatic nerve regeneration and functional recovery, Journal of Tissue Engineering and Regenerative Medicine, vol. 13 (4), 625-636, 2019. (IF=4.089)

    [51] Sun Y. Y., Chen G. B., Lv Y. G.*, Effects of hypoxia on the biological behavior of MSCs seeded in demineralized bone scaffolds with different stiffness, Acta Mechanica Sinica, vol. 35 (2), 309-320, 2019.

    [50] Sha Y. Q., Yang L., Lv Y. G.*, MGF E peptide improves anterior cruciate ligament repair by inhibiting hypoxia-induced cell apoptosis and accelerating angiogenesis, Journal of Cellular Physiology, vol. 234 (6), 8846-8861, 2019. (IF=3.923)

    [49] Liu M. Y., Lv Y. G.*, Reconstructing bone with natural bone graft: a review of in vivo studies in bone defect animal model, Nanomaterials, vol. 8 (12), 999, 2018. (IF=3.504)

    [48] Zhang B. B., Zhang Y., Zhang X. M., Lv Y. G.*, Suspension state promotes extravasation of breast tumor cells by increasing integrin β1 expression, Biocell, vol. 42 (1), 17-24, 2018.

    [47] Hu Q. X., Liu , M. Y. (co-first author), Chen G. B., Xu Z. L., Lv Y. G.*, Demineralized bone scaffolds with tunable matrix stiffness for efficient bone integration, ACS Applied Materials & Interfaces, vol. 10 (33), 27669-27680, 2018. (IF=8.079)

    [46] Zhang X. M., Yang L., Chien S., Lv Y. G.*, Suspension state promotes metastasis of breast cancer cells by up-regulating cyclooxygenase-2, Theranostics, vol. 8 (14), 3722-3736, 2018. (IF=8.766)

    [45] Xia T. T., Zhao R. Z. (co-first author), Feng F., Song Y. J., Zhang Y., Dong L. L., Lv Y. G.*, Yang L.*, Gene expression profiling of human hepatocytes grown on differing substrate stiffness, Biotechnology Letters, vol. 40 (5), 809-818, 2018.

    [44] Xia T. T., Zhao R. Z., Liu W. Q., Huang Q. P., Chen P. X., Waju Y. N., Mohanad K. A., Lv Y. G.*, Yang L.*, Effect of substrate stiffness on hepatocyte migration and cellular Young’s modulus, Journal of Cellular Physiology, vol. 233 (9), 6996-7006, 2018. (IF=4.080)

    [43] Song Y., Xu K., Yu C., Dong L. L., Chen P. X., Lv Y. G., Chiang M. Y. M., Li L. H., Liu W. Q., Yang L., The use of mechano growth factor to prevent cartilage degeneration in knee osteoarthritis, Journal of Tissue Engineering and Regenerative Medicine, vol. 12 (3), 738-749, 2018. (IF=3.989)

    [42] He J. H., Dong L. L., Xu K., Qian Y. N., Wang C. L., Sha Y. Q., Zhong J. L., Liu W. Q., Lv Y. G., Song Y., Yang L., Mechano growth factor E peptide inhibits melanoma cells invasion and upregulates CHOP expression via endoplasmic reticulum stress, Biotechnology Letters, vol. 40 (1), 205-213, 2018.

    [41] Sha Y. Q., Yang L., Lv Y. G.*, ERK1/2 and Akt phosphorylation were essential for MGF E peptide regulating cell morphology and mobility but not proangiogenic capacity of BMSCs under severe hypoxia, Cell Biochemistry and Function, vol. 36 (3), 113-171, 2018.

    [40] Sha Y. Q., Lv Y. G.*, Xu Z L., Yang L., Hao X. Y., Afandi R., MGF E peptide pretreatment improves the proliferation and osteogenic differentiation of BMSCs via MEK-Erk1/2 and PI3K-Akt pathway under severe hypoxia, Life Sciences, vol. 189, 52-62, 2017.

    [39] Zhang X. M., Lv Y. G.*, Suspension state increases reattachment of breast cancer cells by up-regulating lamin A/C, Biochimica et Biophysica Acta-Molecular Cell Research, in press, 2017. (IF=4.521)

    [38] Xia B., Lv Y. G.*, Dual-delivery of VEGF and NGF by emulsion electrospun nanofibrous scaffold for peripheral nerve regeneration, Materials Science & Engineering C-Materials for Biological Applications, vol. 82, 253-264, 2018. (IF=4.164)

    [37] Chen G. B., Lv Y. G.*, Decellularized bone matrix scaffold for bone regeneration, in Decellularized Scaffolds and Organogenesis (Kursad Turksen eds.), Springer, 2017.

    [36] Chen G. B., Lv Y. G.*, Matrix elasticity-modified scaffold loaded with SDF-1α improves the in situ regeneration of segmental bone defect in rabbit radius, Scientific Reports, vol. 7, 1672, 2017. (IF=4.259)

    [35] Sha Y. Q., Afandi R., Zhang B. B., Yang L., Lv Y. G.*, MGF E peptide pretreatment improves collagen synthesis and cell proliferation of injured human ACL fibroblasts via MEK-ERK1/2 signaling pathway, Growth Factors, vol. 35 (1), 29-38, 2017.

    [34] Lv Y. G.*, Chen C., Zhao B. Y., Zhang X. M., Regulation of matrix stiffness on the epithelial-mesenchymal transition of breast cancer cells under hypoxia environment, The Science of Nature, vol. 104 (5-6), 38, 2017.

    [33] Xia B., Zou Y., Xu Z. L., Lv Y. G.*, Gene expression profiling analysis of low-intensity pulsed ultrasound on induced pluripotent stem cells derived neural crest stem cells, Biotechnology and Applied Biochemistry, vol. 64 (6), 927-937, 2017.

    [32] Chen G. B., Xu R. (co-first author), Zhang C., Lv Y. G.*, Responses of MSCs to 3D scaffold matrix mechanical properties under oscillatory perfusion culture, ACS Applied Materials & Interfaces, vol. 9 (2), 1207-1218, 2017. (IF=7.145)

    [31] Lv Y. G.*, Lin C. W., High mobility group box 1-immobilized nanofibrous scaffold enhances vascularization, osteogenesis and stem cells recruitment, Journal of Materials Chemistry B, vol. 4 (30), 5002-5014, 2016. (IF=4.872)

    [30] Dong C. J., Lv Y. G.*, Application of collagen scaffold in tissue engineering: recent advances and new perspectives, Polymers, vol. 8 (2), 42, 2016. (IF=3.681)

    [29] Song Y., Yu C., Wang C. L., Ma X. S., Xu K., Zhong J. L., Lv Y. G., Sung K. L. P., Yang L., Mechano growth factor-C24E, a potential promoting biochemical factor for ligament tissue engineering, Biochemical Engineering Journal, vol. 105 (Part A), pp. 249-263, 2016.

    [28] Chen G. B., Yang L., Lv Y. G.*, Cell-free scaffolds with different stiffness but same microstructure promote bone regeneration in rabbit large bone defect model, Journal of Biomedical Materials Research Part A, vol. 104 (4), pp. 833-841, 2016. (IF=3.369)

    [27] Chen G. B., Lv Y. G.*, Nanotechnology-based cryopreservation of cell-scaffold constructs: a new breakthrough to clinical application, CryoLetters, vol. 37 (6), 381-387, 2016. (invited review)

    [26] Lv Y. G.*, Nan P. P., Chen G. B., Sha Y. Q., Xia B., Yang L., In vivo repair of rat transected sciatic nerve by low-intensity pulsed ultrasound and induced pluripotent stem cells-derived neural crest stem cells, Biotechnology Letters, vol. 37 (12), pp. 2497-2506, 2015.

    [25] Li H. B., Lei M. X., Luo Z. W., Wu S. C., Zhong L., Xu Z. L., Lv Y. G., Yang L., Mechano-growth factor enhances differentiation of bone marrow-derived mesenchymal stem cells, Biotechnology Letters, vol. 37 (11), pp. 2341-2348, 2015.

    [24] Li H. B., Lei M. X., Yu C., Lv Y. G., Song Y., Yang L., Mechano growth factor-E regulates apoptosis and inflammatory responses in fibroblast-like synoviocytes of knee osteoarthritis, International Orthopaedics, vol. 39 (12), pp. 2503-2509, 2015.

    [23] Chen G. B., Dong C. J., Yang L., Lv Y. G.*, 3D scaffolds with different stiffness but the same microstructure for bone tissue engineering, ACS Applied Materials & Interfaces, vol. 7 (29), pp. 15790-15802, 2015. (IF=6.723)

    [22] Qian Y. N., Li L. H., Jiang C., Xu W., Lv Y. G., Zhong L., Cai K. Y., Yang L.*, The effect of hyaluronan on the motility of skin dermal fibroblasts in nanofibrous scaffolds, International Journal of Biological Macromolecules, vol. 79, pp. 133-143, 2015.

    [21] Lv Y. G.*, Nanofiber-based drug design, delivery and application, Current Pharmaceutical Design, vol. 21 (15), pp. 1918-1919, 2015.

    [20] Chen G. B., Lv Y. G.*, Immobilization and application of electrospun nanofiber scaffold-based growth factor in bone tissue engineering, Current Pharmaceutical Design, vol. 21 (15), pp. 1967-1978, 2015.

    [19] Zhang X. M., Lv Y. G.*, Suspension state promotes the malignant potential of MDA-MB-231 cells, 15th International Congress of Biorheology and 8th International Conference on Clinical Hemorheology, May 24-28, 2015, Seoul, Korea.

    [18] Luo Z., Jiang L., Xu Y., Li H., Xu W., Wu S., Wang Y., Tang Z., Lv Y. G.*, and Yang L.*, Mechano growth factor (MGF) and transforming growth factor (TGF)-β3 functionalized silk scaffolds enhance articular hyaline cartilage regeneration in rabbit model, Biomaterials, vol. 52, pp. 463-475, 2015. (IF=8.557)

    [17] Li L. H., Qian Y. N., Lin C. W., Li H. B., Jiang C., Lv Y. G., Liu W. Q., Cai K. Y., Germershaus O., Yang L., The effect of silk gland sericin protein incorporation into electrospun polycaprolactone nanofibers on in vitro and in vivo characteristics, Journal of Materials Chemistry B, vol. 3, pp. 859-870, 2015. (IF=4.726)

    [16] Chen G. B., Lv Y. G.*, Dong C. J., Yang L., Effect of internal structure of collagen/hydroxyapatite scaffold on the fate of mesenchymal stem cells, Current Stem Cell Research & Therapy, vol. 10 (2), pp. 99-108, 2015.

    [15] Lv Y. G.*, Hao X. Y., Sha Y. Q., Yang L., Pretreatment with mechano-growth factor E peptide protects bone marrow mesenchymal cells against damage by fluid shear stress, Biotechnology Letters, vol. 36 (12), pp. 2559-2569, 2014.

    [14] Lv Y. G.*, Zhao P. C., Chen G. B., Sha Y. Q., Yang L., Effects of low intensity pulsed ultrasound on cell viability, proliferation and neural differentiation of induced pluripotent stem cells-derived neural crest stem cells, Biotechnology Letters, vol. 35 (12), pp. 2201-2212, 2013.

[13] Chen G. B., Lv Y. G.*, Guo P., Lin C. W., Zhang X. M., Yang L., Xu Z. L., Matrix mechanics and fluid shear stress control stem cells fate in three dimensional microenvironment, Current Stem Cell Research & Therapy, vol. 8 (4), pp. 313-323, 2013.

[12] Zhang X. M., Lv Y. G.*, Chen G. B., Zou Y., Lin C. W., Yang L., Guo P., Lin M. P., Effect of mild hypothermia on breast cancer cells adhesion and migration, Bioscience Trends, vol. 6 (6), pp. 313-324, 2012.

[11] Tan J., Tian F. F., Lv Y. G.*, Liu W. Q., Zhong L., Liu Y. L., Yang L.*, Integration of QSAR modelling and QM/MM analysis to investigate functional food peptides with antihypertensive activity, Molecular Simulation, vol. 39 (12), pp. 1000-1006, 2013.

[10] Lv Y. G.*, Zou Y., Yang L., Theoretical model for thermal protection by microencapsulated phase change micro/nanoparticles during hyperthermia, Heat and Mass Transfer, vol. 58 (4), pp. 573-584, 2012.

[09] Lv Y. G.*, Zou Y., Yang L., Uncertainty and sensitivity analysis of property of phase change micro/nanoparticles for thermal protection during cryosurgery, Forschung im Ingenieurwesen-Engineering Research, vol. 76 (1-2), pp. 41-50, 2012.

[08] Tian F., Lv Y. G. (co-first author), Yang L., Structure-based prediction of protein-protein binding affinity with consideration of allosteric effect, Amino Acids, vol. 43 (2), pp. 531-543, 2012.

[07] Tian F., Lv Y. G. (co-first author), Zhou P., Yang L., Characterization of PDZ domain-peptide interactions using an integrated protocol of QM/MM, PB/SA, and CFEA analyses, Journal of Computer-Aided Molecular Design, vol. 25 (10), pp. 947-958, 2011.

[06] Lv Y. G.*, Zou Y., Yang L., Feasibility study for thermal protection by microencapsulated phase change micro/nanoparticles during cryosurgery, Chemical Engineering Science, vol. 66 (17), pp. 3941-3953, 2011.

[05] Lv Y. G., Cheung N. K., Fu B. M., A pharmacokinetic model for radioimmunotherapy delivered through cerebrospinal fluid for the treatment of leptomeningeal metastases, Journal of Nuclear Medicine, vol. 50 (8), pp. 1324-1331, 2009.

[04] Lv Y. G., Liu J., Gao Y. H., Xu B., Modeling of transdermal drug delivery with a microneedle array, Journal of Micromechanics and Microengineering, vol. 16 (11), pp. 2492-2501, 2006.

[03] Lv Y. G., Huai X. L., Wang W. W., Study on the effect of micro geometric structure on heat conduction in porous media subjected to pulse laser, Chemical Engineering Science, vol. 61 (17), pp. 5717-5725, 2006.

[02] Lv Y. G., Liu J., Zhang J., Theoretical evaluation of burns to the human respiratory tract due to inhalation of hot gas in the early stage of fires, Burns, vol. 32 (4), pp. 436-446, 2006.

[01] Lv Y. G., Deng Z. S., Liu J., 3-D numerical study on the induced heating effects of embedded micro/nanoparticles on human body subject to external medical electromagnetic field, IEEE Transactions on NanoBioscience, vol. 4 (4), pp. 284-294, 2005.


Book chapters and books:

[03] Yang L., Lv Y. G., Song G. B., Biomechanics and Regeneration, in Regenerative Medicine (Editors, Fu X. B. et al.,), People’s Medical Publishing House, 2013. (in Chinese)

[02] Yang L., Lv Y. G., A Review on the Frontier Research on Biomedical Engineering, in The 2012 Annual Report of Medical Science and Technology Development in China (Editors, Chinese Academy of Medical Sciences), Science Press, 2012. (in Chinese)

[01] Lv Y. G., Multiscale Thermal Response of Biological System-A Field of Full Opportunities and Challenge, in Symposia of Excellent Doctoral Dissertation of Chinese Academy of Sciences 2007 (Editors, Bai C. L.), Science Press, 2008. (in Chinese)


Patents

[08] Lv Y. G. ,Lin C. W.,Zou Y.,ZL 201310271920.2

[07] Lv Y. G. ,Dong C. J.,Zou Y.,ZL 201210417903.0

[06]Lv Y. G. ,Zou Y.,Yang L.,ZL 201110286443.8

[05] Lv Y. G. ,Yang L.,ZL 201010191017.1

[04] Liu J.,Lv Y. G. ,ZL 200410008745.9

[03] Liu J.,Lv Y. G. ,ZL 03137561.8

[02] Liu J.,Lv Y. G. ,ZL 200310122439.3

[01] Yang L.,Liu E. F.,Xu W.,Peng Y. J.,Wang Y. Q.,Mohanad Khalid Ahmed,Lv Y. G. ,ZL 201110177957.X